STUDY OF HYPERSENSITIVITY REACTIONS TO COVID-19 VACCINES
Alicia Armentia, Maria San Miguel, Angel San Miguel*, Daniel Arévalo, Aurora Sacristán, Román Betancort and Ana Cano
ABSTRACT
COVID -19 vaccines have been mild to moderate and of short duration in our health area. These include fever, tiredness, headache, muscle pain, chills, nausea, diarrhea, and pain at the injection site. The chance of any of these side effects depending on each COVID-19 vaccine, and vaccines are constantly monitored for unusual side effects. In this study we assess the tests performed in the Allergy Unit of our Hospital, on patients referred to rule out a hypersensitivity reaction that could jeopardize the next dose. Of the 511 patients scheduled for vaccination at the Río Hortega University Hospital (HURH) in the West Valladolid Health Area, only 459 (89.8%) attended. Of which, 93.7% (CI 91.3-96) did not suffer/report hypersensitivity reactions. And of those that did, only 0.4% (95% CI: 0.05-1.56) were serious, and none were fatal. We conclude that there are no major limitations to the administration of the COVID vaccine in the general population or in the allergic or atopic population. It is to be expected, after the administration of the vaccine, the appearance of pain at the puncture site of high intensity. And there may be an association between the presence of fever and the positive result of immunoallergic tests.
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