World Journal of Pharmaceutical
and Medical Research

( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Pharmaceutical and Medical Research and Technology
An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)
ISSN 2455-3301
IMPACT FACTOR: 6.842

ICV : 78.6

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Abstract

VULVAR ANGIOFIBROMA: CLINICAL AND HISTOLOGICAL ASPECTS OF THIS RARE AND STILL LITTLE-KNOWN ENTITY

Bennani Zineb*, Souradi Houda, Ameqrane Fatima, Yousfi Mounia and Bargach Samir

ABSTRACT

Cellular angiofibroma is a rare benign mesenchymal lesion with a predilection for the genital region, although rare cases have been reported in the pelvic and extrapelvic regions. It mostly affects women in their fifties. Histologically, Cellular angiofibroma is characterized by two principal components: bland spindle cells and abundant prominent small to medium-sized vessels. The characterization by immunohistochemistry is helpful in distinguishing cellular angiofibroma from other mesenchymal lesions. The treatment requires a simple local excision due to low recurrences of the local lesion and no chances of metastasizing. The current study concerns a 52-year-old patient who had two angiofibromas for one year, one on the mons pubis and the other on the right labia majora. The treatment consisted of a simple excision, and the follow-up was unremarkable.

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