MIXED MUCINOUS CARCINOMA OF BREAST – A CASE REPORT
Dr. Benmouna Imane*, Slaoui Aziz, Cherradi Soukaina, Pr Lakhdar Amina, Pr Zeraidi Najia and Pr Baidada Aziz
ABSTRACT
Mucinous carcinoma (MC) is a rare variant of invasive breast cancer accounting for 1-7%. It is most commonly seen in perimenopausal and postmenopausal women. MC is represented by the presence of large extracellularmucin pools. Based on the mucin content two main subtypes are identified: Pure Mucinous Carcinoma(PMC) and Mixed Mucinous Carcinoma (MMC). MC shows fewer axillary lymph node me-tastases and more frequent ER expression, and has a lowfrequency of androgen receptor and low incidence of an-drogen receptor with ER and/or PR co-expression whencompared to intraductal invasive carcinoma. We report the case of a 52-year-old patient with a 6 month disease course characterized by the appearance of a slow-growing tumor in the right upper outer quadrant of the right breast, in which the core biopsy showed mucinous breast carcinoma of a low nuclear grade. The patient underwent right modified mastectomy with right axillary dissection and was diagnosed as mixed type of mucinous carcinoma breast by histopathological examination. It was confirmed by immunohistochemistry which showed positivity for ER, PR and negativity for Her2neu.
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