Abstract

Dr. Silkam A. Sangma*, Dr. Mahadevamma L. and Dr. Kyrshanlang Warshong

ABSTRACT

Introduction: Diabetes Mellitus is now recognized as a major chronic public health problem throughout the world. Diabetic Mellitus is the leading cause of chronic kidney disease and a major source of morbidity and mortality in patients with established Chronic Kidney Disease. Methodology: This was a Prospective and Observational study in which 80 subjects were enrolled based on the criteria, and was assessed and evaluated by utilised a suitable statistical method. Results: Among 80 patients the majority of study subjects 62 (77.5%) were male and 33 (41.3%) were belonged to the age group of 61-70 years out of which 14 of them were obese patients. The prescription pattern showed short acting insulin was prescribed at a higher rate of 20 (15.5%) patients followed by Long acting insulin 18 (14%) and among oral anti-diabetic drugs, Dipeptidyl-peptidase-4 inhibitors 39 (30.2%) with vildagliptin itself prescribed in 19 (14.7%) patients, 2nd generation of sulfonylurea 12(9.3%), alpha-glucosidase 06 (4.7%), SGLT2 inhibitor 06 (4.7%) and combination of 2nd generation sulfonylurea + biguanide 07 (5.4%). Conclusion: Among all the hypoglycemic drugs, the insulin was highly preferred as monotherapy as well as combination therapy over all oral hypoglycemic agents to control the elevated and type -2 glycemic level and vildagliptin accounted for the most commonly prescribed Oral hypoglycemic agents. In the 2nd generation of sulphonylureas class, glimepiride and glipizide were mostly prescribed. This study monitored and evaluated toward the achievement of rational drug use.