World Journal of Pharmaceutical
and Medical Research

( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Pharmaceutical and Medical Research and Technology
An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)
ISSN 2455-3301
IMPACT FACTOR: 6.842

ICV : 78.6

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Abstract

A STUDY ON ANTIPLATELET MEDICATION USED IN CARDIOVASCULAR DISEASE

Suney Sen*, Mahadevamma L. and Akash Nair M.

ABSTRACT

Cardiovascular diseases are the leading cause of death globally. A cardiovascular disease is a group of heart and blood vessels disorders that is the most frequent diagnosis in elderly patients. Antiplatelet therapy is intended to prevent and reverse platelet aggregation in arterial thrombosis in high-risk CVD patients. A study on the antiplatelet medication used in cardiovascular diseases Methodology: This was a prospective and observational study that was performed on 90 subjects, in the cardiology department. Out of 90 patients, 67 were male (74.4%) and 23 were female (25.6%). The age distribution shows that patients aged above 60 years were more predominantly using antiplatelet medication. Based on the distribution of therapy 35 patients were prescribed monotherapy (39%), 55 patients were prescribed with combination therapy (61%). Aspirin was prescribed as monotherapy (37.8%), whereas aspirin & clopidogrel as combination therapy (43%) were prescribed to get better therapy outcomes (100% recovered). Most commonly found ADR was GI bleeding because of Aspirin and risk factors included obesity (96.70%) followed by hypertension, Diabetes mellitus and age. This study reveals that due to gender, an increase in age & changes in social habits leads to CVD. Aspirin & clopidogrel were more useful combination therapy than monotherapy aspirin. Finally, we concluded that combination therapy has better recovery outcomes in CVD treatment. Most ADRs were found in monotherapy.

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