RECENT APPROACHES AND TECHNIQUES FOR THE DEVELOPMENT OF INTRA-NASAL DRUG DELIVERY SYSTEM (INDDS) AND ITS CONTRIBUTION IN THERAPEUTIC MANAGEMENT
Suraj Mandal*, Km. Shiva, Sweta Goel, Bhakti Sudha Pandey, Sanjeev Kumar, Ram Nivas, Pragati Saxena, Himani Gururani and Abhishek Mishra
ABSTRACT
The nasal drug delivery system (NDDS) has used it as an important alternative to the availability of essential drugs. The intranasal segment contains a large area, high pressure, fast acting septum, preventing the first aspiration, the invasive layer of the endothelial and pericardial layers. It has been widely used in recent years for a variety of drugs, including peptides, protein supplements, and simple solutions for nasal congestion. This research article covers the importance, technology, and benefits of nasal mail. Here, several systems are tried to make the building at the time of intranasal injection to produce further absorption of the intranasal drug. In this research article, we discuss the benefits of bioadhesive drugs submitted to the Nasal Medical Association. The transporter (eg, nanoemulsions, microspheres, liposomes, and gels) contains a highly bioadhesive material which improves contact with the nasal mucosa. This mode of transport prevents the medicine from damaging nasal secretions and controls the rate at which the medicine is secreted from the nose.
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