World Journal of Pharmaceutical
and Medical Research

( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Pharmaceutical and Medical Research and Technology
An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)
ISSN 2455-3301
IMPACT FACTOR: 6.842

ICV : 78.6

World Journal of Pharmaceutical and Medical Research (WJPMR) has indexed with various reputed international bodies like : Google Scholar , Index Copernicus , SOCOLAR, China , Indian Science Publications , Cosmos Impact Factor , Research Bible, Fuchu, Tokyo. JAPAN , Scientific Indexing Services (SIS) , UDLedge Science Citation Index , International Impact Factor Services , International Society for Research Activity (ISRA) Journal Impact Factor (JIF) , International Innovative Journal Impact Factor (IIJIF) , Scientific Journal Impact Factor (SJIF) , Global Impact Factor (In Process) , Digital Online Identifier-Database System (DOI-DS) , Science Library Index, Dubai, United Arab Emirates , Eurasian Scientific Journal Index (ESJI) , International Scientific Indexing, (ISI) UAE , IFSIJ Measure of Journal Quality , Web of Science Group (Under Process) , Directory of Research Journals Indexing , Scholar Article Journal Index (SAJI) , International Scientific Indexing ( ISI ) , Scope Database , Academia , 

Abstract

A REVIEW ON ORAL DRUG DELIVERY SYSTEM AND ITS EVALUATION PARAMETERS

Kerryn Joseph A. D. Silva, Suresh N.*, Preethi Fernandiz and S. Srinivasan

ABSTRACT

Oral drug delivery is the most preferred administration route due to noninvasive, high patient compliance, convenient to handle, and does not require any specific sterile conditions. However, some of the drugs administered orally face several physical, biological, and biochemical barriers which lower the therapeutic efficacy of the drugs before getting absorbed into the systemic circulation. Oral medication is the most common form of drug administration because of advantages such as convenience of drug administration via the oral route, patient preference, cost-effectiveness, and ease of large-scale manufacturing of oral dosage forms. Around 60% of established small-molecule drug products available commercially are administered via the oral route. Current estimates indicate that oral formulations represent about 90% of the global market share of all pharmaceutical formulations intended for human use. The delivery systems are mainly based on natural or synthetic materials containing properties relating to absorption enhancer, pH-responsive, stimulation of the living cells. Bioinspired and biomimetic systems are biocompatible, biodegradable, nontoxic, selective, and specific, thus considered as excellent oral drug delivery tools. These systems are copied or modified from natural sources and utilized for oral drug delivery applications. They are very much capable of protecting the drug or therapeutics from GI acidic and enzymatic degradation and release adequately in the targeted site, enhance the drug delivery and ultimately produces the desired pharmacological action.

[Full Text Article]    [Download Certificate]

Powered By WJPMR | All Right Reserved

WJPMR