World Journal of Pharmaceutical
and Medical Research

( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Pharmaceutical and Medical Research and Technology
An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)
ISSN 2455-3301
IMPACT FACTOR: 6.842

ICV : 78.6

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SJIF Impact Factor: 6.842

Abstract

FORMULATION, DEVELOPMENT AND EVALUATION OF FAST DISSOLVING ORAL FILM OF ANTI-MIGRAINE DRUG

*Ramji Kurmi, Dr. Kuldeep Ganju, Devendra S. Lodhi and Khushi Chouksey

ABSTRACT

The fast-dissolving oral films of Rizatriptan benzoate prepared using different film- forming materials by the solvent-casting method which is simple and cost effective. Films showed satisfactory drug dissolution and acceptable physico-mechanical characteristics. Amongst all formulae, the formulation F7 showed the highest dissolution rate. F7 was concluded as optimized formulation because of it showed suitable and satisfactory physico-mechanical properties when compared with marketed formulation. Films were found to be stable at stability conditions. In the present work, it can be concluded that the fast-dissolving films formulation can be an innovative and promising approach for the delivery of Rizatriptan for the treatment of migraine.

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