Abstract

Himani Jaisinghani*

ABSTRACT

Improving oral bioavailability of medicine those given as solid dosage forms remains a challenge for the formulation of scientists because of solubility problems. The dissolution rate can be the rate-limiting process within the absorption of a drug from a solid dosage sort of relatively insoluble drug. Therefore, a rise in the dissolution of poorly soluble drugs by a solid dispersion technique presents a challenge to formulation scientists. Solid dispersion methods have pulled in significant enthusiasm for improving the dissolution rate of exceptionally lipophilic drugs, along these lines improving their ease of use by decreasing drug molecule size improving wettability, and forming amorphous particles. The term solid dispersion is handling a gaggle of solid products which is consisting of a minimum of two different components, generally a hydrophilic inert carrier or matrix and a hydrophobic drug. The historical background of solid dispersion technology, has limitations, classification, and various preparation techniques with its advantages and drawbacks. This review also discusses the recent advances within the field of solid dispersion technology. Supported the prevailing results and authors’ reflection, this review gives rise to reasoning and suggested choices of carrier or matrix and solid dispersion procedure.