Abstract

Dr. Sharma Kanchan*

ABSTRACT

The research work entitled “A Comparative Pharmaceutico-Analytical Study of Gunja Taila and Durvadi Taila in Darunak w.s.r. to Their Antifungal Activity in Dandruff” was planned to compare the efficacy of two formulations based on In vitro Anti-Fungal activity analysis. Therefore, samples of Gunja Taila and Durvadi Taila were prepared with their conceptual references. Both the samples were analyzed based on Organoleptic Parameters, i.e.,Appearance ,Colour ,Odour, Touch, etc. and Physico-chemical Parameters i.e Weight per milliliter, pH, Iodine value, Peroxide value, Saponification value, Acid value, Viscosity, TLC & Refractive index. The findings for these parameters were found to be satisfactory for quality assurance. Assay of heavy metals (Pb, Cd, As, Hg),Total bacterial count and Total fungal count are under the permissible limit depicted in the study. Specific pathogens and aflatoxins (B1, B2, G1, G2) are absent in all samples. The antifungal study of GunjaTaila and Durvadi Taila was seen on Malassezia furfur (MTCC NO: 1374), Trichophyton rubrum: (MTCC NO 296) and Candida albicans(MTCC NO: 183) strains. It is determined by the „Well-diffusion method.? By observing the values in the two samples, the activity index value of GunjaTaila was found to be greater than 0.5, indicating a significant antifungal activity against the defined fungi. In contrast, the Durvadi tail activity index remains below 0.5, which shows its less activity against the selected strains.