SYNTHESIS AND CHARACTERISATION OF NOVEL MANNICH BASE BENZIMIDAZOLE DERIVATIVES
G. Umarani*, Dr. V. Niraimathi, M. Bakyalakshmi
ABSTRACT
Benzimidazole is a heterocyclic aromatic organic compound. Synthesis of novelmannich base 2-substituted benzimidazole derivatives by microwave irradiation method in the presence of glacial acetic acid used as a catalyst. Microwave induced organic reaction enhancement(MORE) is a simple, clean, fast, efficient and economical method for the synthesis of organic chemicals. This technique can reduce the reaction time from hours to minutes. Benzimidazole plays an important role in medicinal chemistry and shows various pharmacological action.
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