World Journal of Pharmaceutical
and Medical Research

( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Pharmaceutical and Medical Research and Technology
An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)
ISSN 2455-3301
IMPACT FACTOR: 6.842

ICV : 78.6

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Abstract

ANTIPLASMODIAL ACTIVITY AND PHYTOCHEMICAL SCREENING OF MONODORA TENUIFOLIA AND OXYANTHUS UNILOCULARIS TWO TRADITIONAL PLANTS.

Kipré Gueyraud Rolland*, Kamagaté Mohamed Lamine, Offoumou Rostand M’Baï, Bouablé Guy Martial, Silué Kigbafori Dieudonné, Zirihi Guédé Noel, Djaman Allico Joseph

ABSTRACT

Medicinal plants are currently being evaluated as source of promising antimalarial agents. Plant extracts contain phytochemical constituents for miscellaneous medicinal activities which are bioactive in nature. There is growing interest in the use of plants for the treatment and prevention of malaria. In this study, we have evaluated the claimed antimalarial properties of four extracts from two plants utilized in traditional malaria remedies and we have investigated phytochemical screening. Schizontocidal activity was measured using a standard in vitro assay, with clinical Plasmodium falciparum isolates. All the 4 extracts showed a good activity on clinical isolate. All extracts contained alkaloids, flavonoids, polyphenols, polyterpenes and sterols.

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