ANTIPLASMODIAL ACTIVITY AND PHYTOCHEMICAL SCREENING OF MONODORA TENUIFOLIA AND OXYANTHUS UNILOCULARIS TWO TRADITIONAL PLANTS.
Kipré Gueyraud Rolland*, Kamagaté Mohamed Lamine, Offoumou Rostand M’Baï, Bouablé Guy Martial, Silué Kigbafori Dieudonné, Zirihi Guédé Noel, Djaman Allico Joseph
ABSTRACT
Medicinal plants are currently being evaluated as source of promising antimalarial agents. Plant extracts contain phytochemical constituents for miscellaneous medicinal activities which are bioactive in nature. There is growing interest in the use of plants for the treatment and prevention of malaria. In this study, we have evaluated the claimed antimalarial properties of four extracts from two plants utilized in traditional malaria remedies and we have investigated phytochemical screening. Schizontocidal activity was measured using a standard in vitro assay, with clinical Plasmodium falciparum isolates. All the 4 extracts showed a good activity on clinical isolate. All extracts contained alkaloids, flavonoids, polyphenols, polyterpenes and sterols.
[Full Text Article] [Download Certificate]