Abstract

Mariame Lakhrissi*, Soumia Benchekroun, Imane Jroundi, Naima El Hafidi and Chafiq Mahraoui

ABSTRACT

The pediatric multisystem inflammatory syndrome has been described as a new manifestation of SARS-CoV-2 infection in children and adolescents. We aim through this retrospective study to describe the epidemiological, clinical, biological, therapeutic and evolutionary characteristics of our patients. 16 cases were identified in the pneumo-allergology and infectious diseases department at the children's hospital in Rabat from November 26th, 2020 to February 24th, 2021.The median age was 6.5 years, with a sex ratio = 1.6. Mucocutaneous manifestations were present in all cases. Gastrointestinal symptoms were present in 69% of cases (11 patients), while respiratory symptoms were present in 4 patients (25%). Biologically, inflammatory markers were elevated in all patients. SARS-CoV-2 reverse transcription polymerase chain reaction (RT-PCR) results were negative in all patients, while SARS-CoV-2 serology was positive in 15/16 patient (94%). Cardiac involvement was present in 37% of cases (6 patients) including myocarditis in 19% of cases (3 patients) and coronary involvement in 31% of cases (5 patients). Most of the characteristics of our MIS-C patients were similar to those in the literature, but more studies are needed to confirm these results and better understand this new entity.