PHYTOCHEMICAL ANALYSIS AND IMMUNOMODULATORY ACTIVITY OF ASANA (PTEROCARPUS MARSUPEUM ROXB.) - AN INVITRO STUDY
Dr. Priya Patil* and Dr. Shashidhar Naik
ABSTRACT
Introduction: Due to increasing side effects of available modern medicines, Immunomodulation using Ayurvedic drugs specially Rasayana drug will be helpful for people in day to day life. Asana has been mentioned as Rasayana dravya by many Acharyas. Therefore Asana (Pterocarpus marsupium) is expected to have immunomodultory activity apart from its other physiological activities. Aims and objective: This study is undertaken “To Evaluate Immunomodulatory activity of Asana (Ptreocarpus marsupeum) in-vitro method. Materials and methods: The immunomodulaton activity of Asana (Pterocarpus marsupium) was evaluated using Nitrobluetetrazolium Test (NBT), Neutrophil locomotion & Chemotaxis test, Phagocytosis and candidacidal assay. Result: Immunomodulation assay showed that the Asana (pterocarpus marsupium) significantly facilitates neutrophil locomotion towards the stimulus or infected site, potentiates neutrophil to kill foreign organism and stimulate of neutrophil for phagocytic activity. From above results of immune-modultory assay with three parameters it is noted that the extract of heart wood of Asana (pterocarpus marsupium) shows significant immune-modulatory activity.
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