ADULT GRANULOSA CELL TUMOR OF THE OVARY: A CASE REPORT
*Dr. Bouterfas M., Bennani A., Serroukh Mohamed M., Yousfi M. and Bargach S.
ABSTRACT
Adult-type granulosa cell tumors (AGCTs) belong to the sex cord-stromal group of ovarian tumors and account for 2-5% of ovarian neoplasms. Histopathology remains the gold standard fo rmaking a diagnosis of GCTs. Recent evidence has shown association of this tumour with Forkhead box L2 gene mutations.Surgery is the mainstay of treatment. Chemotherapy and/or radiotherapy are considered in patients with advanced stage or with unresectable recurrent disease. Granulosa cell tumors are well known for late recurrence and the stage at time of diagnosis is the only prognostic factor that is unequivocally related to survival.
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