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World Journal of Pharmaceutical
and Medical Research

( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Pharmaceutical and Medical Research and Technology
An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)
ISSN 2455-3301
IMPACT FACTOR: 5.922

ICV : 78.6

Abstract

CORRELATION OF DNA DAMAGE AND OBSTETRIC COMPLICATIONS IN PERINATAL ASPHYXIA

A. Manoj*, B. Vishnu Bhat, C. Venkatesh and Z. Bobby

ABSTRACT

The current study was conducted to assess the correlation between DNA damage and Obstetric complications in Perinatal Asphyxia. Among eighty asphyxiated babies were examined and sixty healthy controls were participated in this case control study, 69 had obstetric complications (86.2%). The DNA damage was significantly different between asphyxiated babies with obstetric complication and control babies without obstetric complications (p<0.001). Serum Malondealdehyde (MDA) estimation was significantly more in obstetric complicated babies than control babies (p <0.001). Clinical parameters such as Apgar score and Sarnat and Sarnat score were significantly correlated with Obstetric complications (p<0.001). Comet tail length and Percentage of DNA in tail was significantly associated with Obstetric complications and Maternal Illness(p<0.001).

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