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World Journal of Pharmaceutical
and Medical Research

( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Pharmaceutical and Medical Research and Technology
An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)
ISSN 2455-3301
IMPACT FACTOR: 5.922

ICV : 78.6

Abstract

PHYTOSOMES: INNOVATIVE DRUG DELIVERY SYSTEM FOR EFFECTIVELY DELIVERING BIOACTIVE PHYTOCONSTITUENTS AND PLANT EXTRACTS

Kamini Kashyap*

ABSTRACT

Herbal medications with a large concentration of active constituents have strong bioactivity in vitro but weak in vivo bioactivity owing to poor lipid solubility and molecule scale. As a result, the active components of the herbal extract are badly absorbed and bioavailable. A phyto-phospholipid complex vesicle (Phytosomes) is a promising modern strategy for increasing the bioavailability of herbal extracts and phytoconstituents in pharmaceuticals. Phytosomes are advanced herbal formulations that include the bioactive phytoconstituents of herbal extracts and have the capacity to move from a hydrophilic to a lipophilic state of the cell membrane, resulting in a stronger pharmacokinetic and pharmacodynamic profile than traditional herbal extracts. They can be made in a number of medication types, including suspensions, tablets, creams, and gels. This article discusses recent advances in phytosomes, as well as their use in different standardized herbal extracts, with the aim of providing comprehensive research on phytosomes as a promising drug delivery mechanism.

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