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World Journal of Pharmaceutical
and Medical Research

( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Pharmaceutical and Medical Research and Technology
An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)
ISSN 2455-3301
IMPACT FACTOR: 5.922

ICV : 78.6

Abstract

JRK’S YELATHI CHOORNAM TABLET, EFFECTIVE FOR GASTRIC ACID NEUTRALIZATION AND INCREASED PROTEIN ABSORPTION

Amruthavalli G. V.*, Aruna V. and Gayathri R.

ABSTRACT

Introduction: Yelathi choornam tablet is indicated for acid peptic diseases. Acid peptic diseases or acid peptic disorders are the collective term for the collection of diseases that involves acid production in the stomach and nearby parts of the gastrointestinal tract. Pepsin is a major enzyme that plays an important role in the digestion and is active only at lower pH. Methodology: Efficacy of Yelathi choornam tablet and its influence on pepsin in improving the digestion and absorption was estimated by (1) Pepsin degradation assay by Lowry method. (2) Proteolytic activity of pepsin. Results: Yelathi choornam tablet did not degrade the pepsin and also showed better proteolytic activity even at high pH. Discussion and Conclusion: The present study proves that Yelathi choornam tablet is effective in acid peptic diseases and enhance the pepsin activity even at high pH. Details are presented in the paper.

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