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World Journal of Pharmaceutical
and Medical Research

( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Pharmaceutical and Medical Research and Technology
An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)
ISSN 2455-3301

ICV : 78.6



Dr. Maryam*, Mohammadi Fizza Khan, Ramsha Farheen, Heerat Fatima and Masarrath Unnisa


Miller Fisher Syndrome (MFS) is particularly a subtype of Gullian Barré syndrome (GBS) and is distinguished based on the cardinal signs i.e., ophthalmoplegia, ataxia and areflexia. It is also called Fisher’s Syndrome and was first recognized by James Collier in the year 1932. The cardinal features were also given by James Collier. The name Miller Fisher Syndrome came after Charles Miller Fisher first reported it in 1956 as a particular variant of Gullian Barré syndrome (GBS). Here, we are writing a case of a patient who not only experienced the primary triad of symptoms but also, giddiness, diplopia and headache. The patient is also a known case of hypothyroidism and hypertension. The diagnosis of MFS was made by taking into account the triad of symptoms, CSF analysis which gave slightly elevated protein levels and MRI of brain which showed mild prominence of sulcal, cisternal and ventricular systems. The patient was treated with corticosteroids and certain symptomatic treatments were given to ease the giddiness and headache that the patient was experiencing. Also, the patient was given gait training, deep breathing exercises and ambulation and balance training to make him regain his muscle strength and ability to walk independently.

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