World Journal of Pharmaceutical
and Medical Research

( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Pharmaceutical and Medical Research and Technology
An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)
ISSN 2455-3301
IMPACT FACTOR: 6.842

ICV : 78.6

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Abstract

A PROSPECTIVE COHORT STUDY OF TETANUS; ITS MANAGEMENT AND ASSOCIATED RISK FACTORS

*Hafiz Muhammad Asad Shakeel, Muhammad Sohail and Muhammad Umer Ali Ayub

ABSTRACT

Objectives: Our primary aim of this research was to assess the risk factors and treatment of tetanus and recovery techniques. Design & Duration: We were completed from October 2019 through March 2020 in six months in DHQ Hospital Faisalabad. Subjects and Methods: A total of 90 patients admitted by OPD or emergency department to the hospital were studied. There were 15-30 years of age. A pre-designed proforma was used to record information from each patient. In order to include patients in the study, the patients or their attendants had written consent. Research consent was also obtained from the hospital's medical superintendent. Microsoft Office (version 20) data has been analyzed and the results have been expressed in tables and charts. 95 percent was the confidence interval and 5 percent was the margin for error. Under 0.055, the P-value was considered. Calculated frequency, percentages and means. Using the WHO software, the sample size was determined. Results: It studied a total number of ninety patients, including fifty males patients and forty females patients. With an average of 30 out of 90 dying patients, the total death rate was 33 percent. The ICU continuously monitored these cases. Intubation and mechanical ventilation occurred in patients who had respiratory distress. In these cases, the risk factors were septic abortions, thorn pickles, road accidents, household traumas, abscesses, ulcers or burns, farm injuries, and surgery history during the last two weeks. 24 (60 per cent) of 40 females were at high risk, and 16 (40 per cent) were killed in critical condition despite all actions and support for ventilation. Similarly, 14 (28 per cent) out of 50 male patients were at high risk, and 13 patients (28.2 per cent) died in spite of all preventive measures. Conclusion: In underdeveloped and developing countries, Tetanus is the most life-giving disease. The frequency in South Asia is high. The mortality rate in this study was higher for women than for men. All these cases have not previously been Tetanus vaccinated. Proper vaccination and early diagnosis can significantly reduce death and morbidity. The critical components of management are early diagnosis and rapid management with ICU care and ventilator assistance.

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