World Journal of Pharmaceutical
and Medical Research

( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Pharmaceutical and Medical Research and Technology
An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)
ISSN 2455-3301
IMPACT FACTOR: 6.842

ICV : 78.6

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Abstract

THE STUDY OF COMPARISON OF NIFEDIPINE AND NITROGLYCERINE USE IN PATIENTS OF PRETERM LABOUR

*Rida Ali, Arooj Saqib Malik and Muhammad Hasnain Bashir

ABSTRACT

Objective: The purpose of this analysis is to distinguish between the results of Nitroglycerin and Nifedipine, thus postponing the delivery time. Place and Duration: The study was conducted at the Department of Obstetrics and Gynaecology, DHQ Teaching Hospital, Sargodha, from 1st May 2019 until 1 April 2020. Materials and Methods: The observations included a total of 200 prematurely administered women and divided them between two groups by the lottery method. Group A. Nifedipine and nitroglycerine administered to women were observed until the day of delivery and complications after childbirth were duly observed in the pre-designed Performa. Informed consent was obtained by the participants. To select cases, purposeful non-probability sampling was used. The entry and analysis of SPSS data was conducted (version 10). Results: The average extended pregnancy for Group A was 41.23 hours ± 25.11SD. Of the 100 patients in Group A, 58 (58%) had two days of pregnancy, followed by 23 (23%) patients with one day of extension. Pregnancy prolongation in Group B was observed at 54 (54 percent) days, followed by 17 (17 percent) in patients with 1-day pregnancy prolongation. 19 (19%) women were pregnant for more than two days in Group A and 29 (19%) women were pregnant for more than two days in Group B (29 per cent). The difference in pregnancy length was insignificant in both groups, and p was 0.653. A greater rate of complications was shown in Group B. Group A showed a post-therapy headache of 21 percent. 32 percent of patients accounted for group B. Group A patients were admitted to NICU at 18%, while Group B patients were admitted to NICU at 35%. Conclusion: Nifedipine is useful in the treatment of premature delivery.

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