World Journal of Pharmaceutical
and Medical Research

( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Pharmaceutical and Medical Research and Technology
An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)
ISSN 2455-3301
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Abstract

KHAGESWARA RASA- A KUPIPAKA RASAYAN W.S.R. TO PHARMACEUTICO-ANALYTICAL STUDY

Dr. Praveen Raghuwanshi* and Dr. Nagendra Thakre

ABSTRACT

Ayurveda places great emphasis on prevention and encourages the maintenance of health through close attention to balance in one?s life, right thinking, diet, lifestyle and the use of herbs. Knowledge of Ayurveda enables one to understand how to create this balance of body, mind and consciousness according to one?s own individual constitution and how to make lifestyle changes to bring about and maintain this balance. Rasa shastra is the branch deal with the knowledge which teaches us to purification, process, conversion of the drugs, irrespective of their nature into Rasa like form means in an absorbable, bioavalabile form. Khageswara Rasa is Sagandha, Saagni Kupipaka Rasayana described in R.R.S. containing purified Mercury, Sulphur and Green Vitriol in equal proportions processed with Bhavana of Arjuna Kwatha than preparation of small Balls like pellets from the Bhavita mixture. Finally these pellets are subjected to Kupipaka for 36 hrs. with specific heating patterns, Analytical study of Khageswara Rasa shows weight loss on drying is 1.69 % which indicates the preparation has less moisture value, suggesting its long shelf life. Total Ash value is 22.41%, pH Value is 4.9, XRD report shows that all peaks are of Hg, S and Fe. In the SEM analysis particle size was Maximum 540nm and 440nm was Minimum at 5KX and 335nm, 281.nm at 7KX. This proves that the drug can be easily absorbed. EDX report shows Hg-72.34% and S-27.64% of product optioned from neck of the bottle and product optioned from bottom reports shows Fe-88.25% and S-11.75% of Khageswara Rasa.

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