Abstract

Dr. Rehan Ahmad Khan*, Dr. Yar Jahan and Dr. Mirza Shahryar Baig

ABSTRACT

Objectives: This study's basic aim was the assessment of anemia in rheumatoid arthritis patients, differentiated between the types of anemia and correlation between anemia and duration of rheumatoid arthritis. Material and method: This cross-sectional study was conducted in Sheikh Zayed Hospital Rahim Yar Khan, from January 2019 to November 2019. A total of 100 samples were obtained, among them 50 patients diagnosed with rheumatoid arthritis, 50 samples were collected from healthy subjects as control. Fifty informed male and female consented patients diagnosed with Rheumatoid arthritis were recruited for the study. Rheumatoid arthritis patients with chronic disease (renal failure, heart disease, liver disease, malignant diseases) were also excluded. Result: (60%) of rheumatoid arthritis are anemic and (40%) non-anemic. The result demonstrated that the Hb level, RBCs, and PCV are significantly reduced in anemic rheumatoid arthritis patients than non-anemic rheumatoid arthritis patients with P value (0.000) Hb, RBCs, and PCV. The result also demonstrated that MCH significantly reduced in anemic rheumatoid arthritis patients of compared to non -anemic rheumatoid arthritis patients with P value (0.003) while MCV & MCHC are within a normal range. In anemic rheumatoid arthritis patients, serum ferritin was significantly reduced in 7, while 23 patients have a normal serum ferritin level. Based on a 15?g/L cutoff for ferritin, 23% of anemic rheumatoid arthritis patients have IDA, and 77% have ACD. Conclusion: There are two types of anemia in rheumatoid arthritis patients, IDA and ACD. Anemia of chronic disease is more common as compared to IDA in rheumatoid arthritis patients.