Abstract

Hajar Benzouina*, Dalal Elhamssili, Tarik Bouattar, Loubna Benamar, Rabia Bayahia and Naima Ouzeddoun

ABSTRACT

Introduction: Ig A nephropathy is a glomerulonephritis characterized by a nephrotic syndrome and hematuria with histological evidence of Ig A mesangial deposits. It can be primary or secondary to infections including parasites. We illustrate through this clinical case the renal impairment probably secondary to hydatid disease. Clinical observation: Mr C. A 29 year old is followed for hepatic, splenic and peritoneal hydatidosis. He is admitted to the nephrology department for lower limb oedema, ascites with weight gain of 30 kg. Blood pressure is 130/90mmHg. The rest of the somatic examination is normal. Biologically, there is a nephrotic syndrome with acute renal failure with preserved diuresis (serum creatinine 400 umol/l), microscopic hematuria and leukocyturia. Renal biopsy revealed IgA nephropathy. Treatment is symptomatic based on water depletion by loop diuretics and ultrafiltration in hemodialysis and etiologic based on treatment of hydatidosis with Albendazole. The evolution is marked by the regression of the nephrotic syndrome but persistence of moderate chronic renal insufficiency with a serum creatinine around 180 mmol/l. Conclusion: IgA nephropathy secondary to hydatid disease is a serious form that can progress to end-stage renal disease, hence the importance of rapid management of the infection.