World Journal of Pharmaceutical and Medical Research (WJPMR) has indexed with various reputed international bodies like : Google Scholar , Index Copernicus , SOCOLAR, China , Indian Science Publications , Cosmos Impact Factor , Research Bible, Fuchu, Tokyo. JAPAN , Scientific Indexing Services (SIS) , UDLedge Science Citation Index , International Impact Factor Services , International Society for Research Activity (ISRA) Journal Impact Factor (JIF) , International Innovative Journal Impact Factor (IIJIF) , Scientific Journal Impact Factor (SJIF) , Global Impact Factor (In Process) , Digital Online Identifier-Database System (DOI-DS) , Science Library Index, Dubai, United Arab Emirates , Eurasian Scientific Journal Index (ESJI) , International Scientific Indexing, (ISI) UAE , IFSIJ Measure of Journal Quality , Web of Science Group (Under Process) , Directory of Research Journals Indexing , 

World Journal of Pharmaceutical
and Medical Research

An International Peer Reviewed Journal for Pharmaceutical and Medical Research and Technology
An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)
ISSN 2455-3301

ICV : 78.6



Ananya Raj*, Arpita Biswas, Dr. Dhrubo Jyoti Sen and Dr. Beduin Mahanti


Insulin is involved in regulation of glucose utilization in the body. Inability of the body to synthesize insulin or human cells resistance to insulin leads to a condition called Diabetes mellitus which is characterized by chronic hyperglycemia. There are two types of diabetes; type 1 and type 2. Exogenous supply of insulin is needed consistently for type 1 diabetes treatment and type 2 diabetes also needs to be cured by the exogenous supply of insulin in advance stages of the disease. Insulin Site of administration of insulin injection is equally important for better and safe action of insulin and can be given by intramuscular or intravenous route. Insulin replacement therapy is essential for anyone with type 1 diabetes. Most patients with gestational or type 2 diabetes may also require insulin. The goals of insulin therapy are: to achieve optimal glycemic control without causing hypoglycemia or excessive weight gain and to minimize the impact on lifestyle. The therapeutic goals should be individualized according to patient’s age, disease duration, complications, comorbidities, lifestyle, and expected survival. Early insulins were extracted from the pancreas of pigs and cows but good glycemic control was difficult to achieve because of residual impurities after the purification process. The newer and purer animal insulins are better tolerated and can potentially achieve a level of glycemic control similar to synthetic human insulins. Clinically significant hypoglycemia rates between the human and animal insulins also appear to be similar. This review explores insulin in terms of its historical perspectives, regimens, adverse effect along with the future perspective.

[Full Text Article]

Powered By WJPMR | All Right Reserved