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World Journal of Pharmaceutical
and Medical Research

An International Peer Reviewed Journal for Pharmaceutical and Medical Research and Technology
An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)
ISSN 2455-3301
IMPACT FACTOR: 5.922

ICV : 78.6

Abstract

ISOTRETINOIN: A POTENTIAL TREATMENT FOR COVID-19

Ahmed M. Abbas*, Islam M. Ebrahim, Abdelrahman G. Ramadan and Alaa Rashad Ali

ABSTRACT

The emergence of coronavirus disease-2019 (COVID-19) pandemic and its catastrophic consequences resulted in extreme demand for treatment. Nevertheless, it requires a relatively long time to approve new drugs to be used on humans. Therefore, researchers are reconsidering widely available and already approved drugs to be used in the treatment of COVID-19. This review illustrates the promising effect of isotretinoin in the treatment of SARS-CoV-2 owing to its ability to reduce Angiotensin Converting Enzyme (ACE2) receptor expression and its impact on immunity, androgen receptors, and respiratory diseases.

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