World Journal of Pharmaceutical
and Medical Research

( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Pharmaceutical and Medical Research and Technology
An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)
ISSN 2455-3301
IMPACT FACTOR: 6.842

ICV : 78.6

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Abstract

CLINICAL AUDIT OF PATIENTS WITH CHOLELITHIASIS

Dr. Intikhab Shamshad*, Dr. Alina Altaf, Dr. Kashif Fareed

ABSTRACT

Background: Gallstone is a major health problem worldwide. Cholelithiasis prevalence in Pakistan is about 15 to 20 %. Common risk factors for gallstones formation are old age, female, obesity and diabetes mellitus etc. Aim of study: To evaluate the clinical profile of patients with Cholelithiasis. Methodology: It is a cross-sectional study done at Jinnah Hospital Lahore from August 2017 to January 2018. We enrolled 75 patients in the study of age more than 30 years of age diagnosed as Cholelithiasis to study their clinical profile. All diagnosed patients of gallstones through ultrasound were admitted in ward. Clinical presentation like signs, symptoms and preoperative ultrasound findings of all patients were noted on a performa. Results: Total 75 were admitted studied with the history of Cholelithiasis. The mean age of patient was 45.5±6.48 years and duration of disease was 6.2±2.53. We found that 75% patients in our study were female. Almost 65% patients were from rural background. The clinical features observed were fever 32%, nausea 45%, vomiting 38% jaundice 18%, abdominal pain 92% and dyspepsia 26%. The ultrasound findings among patients were single stone 15%, multiple stone 32%, bile duct stones 15%, thickening of gallbladder 40%, and bile duct dilation 14%. 70% of patients managed by laparoscopic cholecystectomy and 30% by open cholecystectomy. Biochemistry of gallstone was, cholesterol stone 28%, mixed 54% and pigmented 18%. Conclusion: We concluded that incidence of gallstones is high forty year of age with female preponderance. The most common presenting complain was pain and tenderness at right hypochondrium. Ultrasound proved to be best screening test for Cholelithiasis.

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