CHEMISTRY GOES GREEN: A REVIEW ON CURRENT AND FUTURE PERSPECTIVES OF PHARMACEUTICAL GREEN CHEMISTRY
Mona Patel*, Harsha Patel, Shweta Mevada and Ojash Patel
ABSTRACT
Over the past few decades, the chemistry community has been mobilized to develop a new chemistry that is less hazardous to the environment as well as human health. This new approach has received extensive attention and nominated by many names including Green Chemistry, Environmentally Benign Chemistry, Clean Chemistry, Atom Economy and Benign by Design Chemistry. Below all of these different designations there is a movement toward pursuing chemistry with the knowledge that the consequences of chemistry do not stop with the properties of the target molecule or the efficacy of a particular reagent. The practice of chemistry in a manner that maximizes its benefits while eliminating or at least greatly reducing its adverse impacts has come to be known as green chemistry. It focuses on a process (whether carried out in industry or a chemical laboratory) that reduces the use and generation of hazardous substances or by-products. As on today, maximum pollution to the environment is caused by numerous chemical industries. Therefore, attempts have been made to design synthesis for manufacturing processes in such a way that the waste products are minimum, they have no effect on the environment and their disposal is convenient. In pharmaceutical industry, some drugs generate large amount of waste as byproducts during their synthesis which results the low yield in the final products. For carrying out reactions it is necessary that the starting materials, solvents and catalysts should be carefully chosen. Green chemistry play important role in pharmaceutical in developing innovatory drug delivery methods which are less toxic and more useful, effective with minimum side effects and could help millions of patients. In this review, we will also be looking ahead at the immediate and longer-term challenges and opportunities as I now see them in research and in industrial application and also in education and promotion.
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