World Journal of Pharmaceutical
and Medical Research

( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Pharmaceutical and Medical Research and Technology
An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)
ISSN 2455-3301
IMPACT FACTOR: 6.842

ICV : 78.6

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Abstract

PRIMARY NEUROENDOCRINE TUMOUR OF MANDIBLE: A CASE REPORT WITH RADIOLOGICAL AND HISTOPATHOLOGICAL FINDING

Monika Gupta*, Virendra Singh, Anjali Narwal and Rajeev Sen

ABSTRACT

Neuroendocrine tumours (NETs) in the oral and maxillofacial region are extremely rare and accounts for only 4% of all cases. As per literature, 46 cases of NETs of maxillofacial region are reported till date. A sixty-four old male presented with swelling right side of face. Clinical examination revealed expansile swelling in the right mandibular region with intraoral extension causing restriction of jaw movement. Biopsy was performed. Microscopic examination revealed monotonous round to oval cells with hyperchromatic nuclei and scanty eosinophilic cytoplasm, infiltrating the fibrocollagenous connective tissue. Immunohistochemistry was performed. Although of uncommon occurrence, with poor prognosis, histopathology and immunohistochemistry is important and most significant tool in differentiating this tumour from other round cell tumours of this area in view of therapeutic connotation. The present case is one of the rarest possibilities as the provisional diagnosis was completely different to the histopathological diagnosis.

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