Abstract

Rajeev Shah* and Reena Mehta

ABSTRACT

Covid-19 pandemic shocks and locks whole world in year 2019 and 2020. Maximum death occurred in USA followed by Italy and Spain. Here discussion and analysis have been focused on various types of vaccines of Corona virus on basis of its spike antigen S and its corresponding ACE2 receptors on certain type of human cells. The ultimate target of all types of vaccines is to prevent binding of ACE2 receptor to S antigen of corona. The main sources of the latest information of Covid 19 vaccination has been internet websites and social net working like whatsApp and facebook etc. Recently on 28th April, there is a video on facebook that Oxford University, London claimed of finding out live attenuated vaccine which had been on trial basis on 800 human volunteers and they ordered Serum India company, which have the capacity of producing 1.5 billion vaccines every year, expected to be ready by September 2020. If this vaccine will found satisfactory, it would be the fastest vaccine invented ever, as usually five to six years are required in such invention, The cost wise also it will be also very cheap, it will cost about 0.5 cent per vaccine, should be consider ahead of others followed by claim of Germany and UK, the vaccine developed from chimpanzee’s Corona virus is ahead of other type as now they got permission of even testing on human volunteers. Israeli defense lab claimed totally new approach of vaccine, in which rather than injecting a pathogen’s antigen into human body, body has been given genetic code needed to produce that antigen itself. Israel claims this unique vaccine production requires minimum of nine months. The report of Arab news, quoting Italian news agency ANSA, claimed that company Takis isolated antibodies in mice which blocked virus from infecting human cells, which according to us should be not consider as vaccine but is the method of passive immunization and will be useful only in treatment but not for prophylaxis. Australia also claimed to develop monoclonal antibodies but by different technique but is also not vaccine candidate like Italian. Even though whole world community of scientists are working on the finding out of treatment as well as vaccine against Covid 19, till that time social distancing and lockdown only can break the chain of transmission which in turn reduces number of infected patients along with morbidity and mortality in the whole globe.