SHOULD ACE INHIBITORS AND ARBS BE PRESCRIBED OR PROSCRIBED IN COVID-19?
Ravi Kant* and Dr. Mahendra Kumar Meena
ABSTRACT
The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) which have been responsible for current pandemic COVID – 19 disease. This virus competes with the renin-angiotensin-aldosterone system (RAAS) through angiotensin-converting enzyme2 (ACE2), an enzyme that play an important role not only in activation of RAAS but also act as a receptor for virus entry point. This interaction between ACE2 and COVID-19 viruses has been considered as a potential factor in their infectivity, and it is a matter of great concerns about the use of ACEIs/ARBs that might alter ACE2 and may be responsible for vivid outcomes in ongoing COVID-19 pandemic.
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