Abstract

Sandip Agrawal, Dr. Anil Chandewar, Rakesh Tiwle, Dr. Nitin Kochar*

ABSTRACT

Gymnosporia montana (GM) belonging to the family Celastraceae commonly known as Bharatti and Vikalo. It is a shrub or tree growing wild in dry areas and is commonly found in Maharashtra, Gujarat and other part of India. It is widely used in treating sore, ulcer, gastro-intestinal disorders, toothache, and dysentery. The dried powder of leaf of Gymnosporia montana was subjected to the phytochemical screening for the presence of various phytoconstituents like alkaloids, flavonoids, saponins, tannins, anthraquinones, and carbohydrates, etc. Effectiveness of different extracts of leaf of Gymnosporia montana was evaluated (100 and 200 mg/kg; p.o.) against Streptozotocin (STZ) induced diabetes mellitus in rat for blood glucose level and blood parameters. Further, ethanolic extract of the plant was also evaluated (200 mg/kg; p.o.) for glycosylated haemoglobion study. The result of study show ethanol and aqueous extract powder of Gymnosporia montana, an popular herbal drugs, appears to be a safe alternative to reducing blood glucose.