Abstract

Dr. Qaseem Ali Zaidi*, Dr. Khair Un Nisa, Dr. Talha Bin Yousuf

ABSTRACT

Objective: To study lipid profile in cases of hypertension presenting at Sheikh Zayed Hospital Rahim Yar Khan. Material and methods: This descriptive study was conducted at Department of Medicine Sheikh Zayed Hospital Rahim Yar Khan from April 2018 to October 2018. A total of 100 patients admitted with hypertension were the participants of the study. The patients are in the range of 40-80 years. Both known hypertensive patients who were on treatment for a varying period of time and newly diagnosed hypertensive patients were included in the study. Results: Serum TC, TGL, VLDL, LDL, TC/ HDL, LDL/ HDL were significantly elevated in hypertensive group as compared to healthy controls. Serum HDL was low in patients with hypertension as was compared with controls, which was statistically significant. The LDL was raised in obese compared to non-obese patients, which is statistically very significant. TC/ HDL and LDL /HDL were also raised in obese patients which is statistically significant. TC is raised in CVA group, which is statistically highly significant. LDL is raised in CVA group, which is statistically very significant. TC/ HDL and LDL/ HDL are raised in CVA group compared to non-CVA group, which is statistically very significant. TC is raised in IHD group, which is statistically significant. LDL is raised in IHD group, which is statistically very significant. LDL/HDL is raised in men, which is statically significant. Conclusion: There is significant alteration of lipid profile in hypertensive patients as compared to controls. Total cholesterol, LDL cholesterol, triglycerides, VLDL, TC/HDL and LDL/HDL ratios are significantly elevated in patients with hypertension. HDL is significantly reduced in hypertensive patients. Hyperlipidemia is seen in majority of cases of hypertension with Type IIa pattern being the most frequent. Mean TC, LDL, TC /HDL, LDL/ HDL were higher in obese. Mean TC, LDL, TC/ HDL and LDL/ HDL ratios are raised in CVA group. Mean TC and LDL are raised in IHD group.