World Journal of Pharmaceutical
and Medical Research

( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Pharmaceutical and Medical Research and Technology
An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)
ISSN 2455-3301
IMPACT FACTOR: 6.842

ICV : 78.6

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SJIF Impact Factor: 6.842

Abstract

EFFECTS OF SUB-LETHAL EXPOSURE OF LAMBDA-CYHALOTHRIN ON BIRTH OUTCOME OF FEMALE WISTAR RATS

*Iheanacho J.U.I., Onyeka P.I.K., Udujih, H.I., Udujih O.G. and Iwuala C.C.

ABSTRACT

Lambda-Cyhalothrin (LCT) is widely used pyrethroid pesticide for pests control in agriculture, home, health and so on. The aim of this study was to investigate toxicity of sub-lethal doses of Lambda-Cyhalothrin on birth outcome of pregnant female wistar rats (Rattus novergicus). Animals were randomly assigned into four equal groups. Group 1 (control) received normal feed and water. Animals in group 2 to 4 were treated with three concentrations of lambda-cyhalothrin 0.2%, 0.4% and 0.8% respectively through feed and drinking water ad libitum from gestation day 1 through to weaning. The results on litter size indicates a significant dose dependent decrease (p

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