TARGETED THERAPY FOR RENAL CELL METASTATIC CANCER
M. N. Tillashaykhov and L. T. Gaziev*
ABSTRACT
Renal cell carcinoma (RCC) accounts for 2-3% of all malignancies in adults, while the incidence increases in most developed countries: the annual increase is 2.3%.[1] In Russia, in 2017, RCC was first diagnosed in 13556 patients. The standardized incidence rate was 16.87 per 100,000 populations, and the increase in incidence over 10 years was 42.63%. In terms of the rate of increase in the incidence of RCC, it is second only to prostate and thyroid tumors.[2] In 2018 in Uzbekistan, RCC was first diagnosed in 717 patients. The standardized incidence rate was 2.2 per 100 thousand populations.[3] Despite the fact that the majority (up to 70%) of patients with RCC are detected at the stage of localized tumor process, more than half of patients develop metastases after surgical treatment.[4]
[Full Text Article] [Download Certificate]