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World Journal of Pharmaceutical
and Medical Research

An International Peer Reviewed Journal for Pharmaceutical and Medical Research and Technology
An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)
ISSN 2455-3301
IMPACT FACTOR: 5.922

ICV : 78.6

Abstract

BREAST CANCER REVEALED BY PARALYSIS OF THE COMMON OCULOMOTOR NERVE : A CASE REPORT AND REVIEW OF THE LITERATURE

Oubahha Ihsane, Asmouki Hamid*, Ait Souabni Sara, Hajji Ibtissam, Belhaddad Habib, Inzale Nouha, Moutaouakil Abdeljalil and Soummani Abderaouf

ABSTRACT

The metastatic involvement of the orbit in malignant tumors is a rarely diagnosed condition. Breast cancer accounts for the majority of these cases. Breast cancer can metastasize to many sites, but the orbit is an infrequent location and a comparatively rare site of distribution among the ocular area structures. Longer survival of patients with metastatic disease as well as advances in diagnostic imaging may explain the increasing frequency of ocular involvement[1] that occurs in up to one third of breast cancer patients.[2] Bone metastases as a sole metastatic site in breast cancer portend a good prognosis as opposed to visceral disease and are seen frequently in the ER/PR (+) Her2/Neu (?) subset of the disease. Nevertheless, they may present a particular clinical problem if they are neighboring sensitive structures such as the spine or the eye, as in this case, and may need urgent treatment to preserve patient’s quality of life and function. We report the case of a 50-year-old patient who had orbital metastases of an unknown breast cancer. The commonest clinical sign at diagnosis is exophthalmia. Prognosis is usually pejorative once diagnosis is performed. Standard treatment is radiotherapy and requires a multidisciplinary approach.

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