World Journal of Pharmaceutical
and Medical Research

( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Pharmaceutical and Medical Research and Technology
An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)
ISSN 2455-3301
IMPACT FACTOR: 6.842

ICV : 78.6

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SJIF Impact Factor: 6.842

Abstract

MANAGEMENT OF DRUG INDUCED SEXUAL DYSFUNCTION IN MALE RATS BY SILDINAFIL CITRATE

Sridhar S. M.*, Rohit Saraswat, Ashok Kumar B. S., Pradeep Kumar L., Gopisetty Saran

ABSTRACT

Sexual dysfunction is a highly prevalent disease associated with aging as well as with several risk factors including hypertension, heart disease diabetes, depression, drug-related. The present study aimed to investigation the effect of phosphodiesterase inhibitors (Sildinafil Citrate) on sexual behavior parameters like: mount latency (ML), mount frequency (MF), intromission latency and frequency (IL & IF), Ejaculatory Latency(EL) and frequency (EF), post ejaculatory Interval (PEI). The result reveals that treatment with Sildinafil Citrate improves sexual behavior in clomipramine induced sexual dysfunction rats.

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