World Journal of Pharmaceutical
and Medical Research

( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Pharmaceutical and Medical Research and Technology
An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)
ISSN 2455-3301
IMPACT FACTOR: 6.842

ICV : 78.6

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SJIF Impact Factor: 6.842

Abstract

HEMOPOIETIC EFFECTS OF SOME HERBAL EXTRACTS USED IN TREATMENT OF INFANTILE ANEMIA IN CAMEROON

Dr. Beack B. S. Suzanne, Fanta Y. S. Adeline, Kopa K. Theodora, Hadidjatou Dairou, Kojom L. Pradel, Kognou M. Aristide, Ndomou Mathieu, Agbor A. Gabriel, Ngono N. R. Anne* and Tchiegang Clerge

ABSTRACT

The hemopoietic activity of Manihot esculenta, Plastotoma africanum, Ricinodendron heudelotii and Sacoglottis gabonensis extracts used for treatment of infantile anemia were studied on hemolytic anemic rats. Anemia was induced by repeated intraperitoneal injection of phenylhydrazine (40 mg/kg of body weight/day) for two days. A drop in red blood cell count, haemoglobin concentration, and pack cell volume characterized the anemia condition. In addition, the histopathological examination of the bone marrow for blood cells further characterized the anemic condition. Results obtained revealed that oral administration of plant extracts to rats significantly (p

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