World Journal of Pharmaceutical
and Medical Research

( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Pharmaceutical and Medical Research and Technology
An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)
ISSN 2455-3301
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ICV : 78.6

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Abstract

BROWN TUMOR OF THE ORBITAL ROOF, ISOLATED MANIFESTATION OF SECONDARY HYPERPARATHYROIDISM: REPORT OF A CASE

*H. Abourazzek, M. Elanigri, K. Mazouz, Z. Essaadi, M. Derfaoui, I. Lalya, A. Elomrani and M. Khouchani

ABSTRACT

Introduction: Brown tumor is a non-neoplastic lesion, secondary to disturbance in bone metabolism in the context of the primary or secondary hyperparathyroidism. Subject of the Study: We report a clinical case to illustrate the rarity and highlight the clinical, therapeutic and evolutionary characteristics of this condition. Observation: it’s Mr. AE 34 years old, followed in nephrology for chronic renal failure on hemodialysis, consult in ophthalmology for a progressive instalation of exophthalmia without effects on visual acuity. A cranial ct-scan Shows bone mass on the orbital roof, without optic nerve compression. An excisional biopsy of the mass was conducted. Histological examination was in favor of osteoblastic giant cell tumor. Laboratory tests showed hyperparathyroidism. Discussion and Conclusion: brown tumor is a secondary lesion to primary hyperparathyroidism or most often secondary to chronic renal failure. It mostly affects the ratings, pelvis, femur and mandible. Reaching the roof of the orbit is exceptional. A female predominance is noted. Before the non-specic histology, only the association of osteoclastic giant cells hyperparathyroidism can confirm the diagnosis. treatment of hyperparathyroidism alone can lead to the regression of the expansive process.

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