Abstract

Sarika S. Lokhande*, Phalke N. N. and Badadare S. S.

ABSTRACT

Oral drug delivery is the most preferred and expedient option as the oral route provides greatest active surface area among all drug delivery system for administration of various drugs. The attractiveness of these dosage forms is due to consciousness to toxicity and ineffectiveness of drugs when administered by oral predictable method in the form of tablets & capsules. There are several advantages of sustained release drug delivery over conventional dosage forms like improved patient compliance due to less frequent drug administration, maximum consumption of the drug, increased safety margin of potent drug, reduction of fluctuation in steady-state drug levels, decrease in healthcare costs through enhanced therapy and shorter treatment period. The principal goal of sustained release forms is the improvement of drug therapy assessed by the relationship between advantages and disadvantages of the use of sustained release system.