World Journal of Pharmaceutical
and Medical Research

( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Pharmaceutical and Medical Research and Technology
An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)
ISSN 2455-3301
IMPACT FACTOR: 6.842

ICV : 78.6

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Abstract

A STUDY ON RISK OF PRE-EXISTING ANTIPLATELET THERAPY IN INTRACRANIAL HEMORRHAGE AND ASSESSING IMPACT OF PATIENT COUNSELLING IN HEALTH RELATED QUALITY OF LIFE

Dr. Malini Gopinath*, Krishnaja R. J., Lekshmi Johnson Maithyli

ABSTRACT

Background: Intra-cerebral hemorrhage (ICH) is defined as bleeding into the parenchyma of the brain. Aim & Objective: The purpose of the study was to evaluate the risk of pre-existing anti-platelet therapy in causing and worsening of intracranial hemorrhagic patients and to assess the impact of patient counselling in improving their health related quality of life with the aid of a knowledge-attitude questionairre. Materials and Methods: A total of 72 ICH patients into 2 groups such as group A patients without pre existing antiplatelet therapy and group B patients with prior antiplatelet therapy and the relationship of preexisting antiplatelet usage in worsening of ICH is determined by comparative analysis of proportions of several standardised scores.All the participants were interviewed and then an effective counseling was given and evaluates their improvement in heath related quality of life by using EQ-5D questionairre. All statistical analysis was performed with SPSS and Minitab software. Result: By statistical comparison of proportions, after analysing the severity at the admission time, ICH risk score, unfavourable functional outcome and mortality rate were found to be higher in patients on pre-treatment with anti-platelets. Participants had some knowledge about prominent symptoms of ICH (loss of consciousness and paralysis) but they are confused it with stroke. Conclusions: Based on the study, pre-treatment with anti-platelet agents is found to play a role in worsening or unfavourable outcome in patients with Intra-cranial hemorrhage. This study also showed improvement in knowledge and attitude of participants will significantly assists in improving their health related quality of life.

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