World Journal of Pharmaceutical
and Medical Research

( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Pharmaceutical and Medical Research and Technology
An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)
ISSN 2455-3301
IMPACT FACTOR: 6.842

ICV : 78.6

World Journal of Pharmaceutical and Medical Research (WJPMR) has indexed with various reputed international bodies like : Google Scholar , Index Copernicus , SOCOLAR, China , Indian Science Publications , Cosmos Impact Factor , Research Bible, Fuchu, Tokyo. JAPAN , Scientific Indexing Services (SIS) , UDLedge Science Citation Index , International Impact Factor Services , International Society for Research Activity (ISRA) Journal Impact Factor (JIF) , International Innovative Journal Impact Factor (IIJIF) , Scientific Journal Impact Factor (SJIF) , Global Impact Factor (In Process) , Digital Online Identifier-Database System (DOI-DS) , Science Library Index, Dubai, United Arab Emirates , Eurasian Scientific Journal Index (ESJI) , International Scientific Indexing, (ISI) UAE , IFSIJ Measure of Journal Quality , Web of Science Group (Under Process) , Directory of Research Journals Indexing , Scholar Article Journal Index (SAJI) , International Scientific Indexing ( ISI ) , Scope Database , Academia , 

Abstract

HERB, CLIMBAZOLE + ZINC PYRITHIONE SYNERGY TO DEAL DRUG RESISTANCE

Amruthavalli G. V.*, Satarupa Mukherjee, Aruna V. and Gayathri R.

ABSTRACT

Background: The present study deals with the importance of herbs in fortifying the anti-dandruff efficacy of Climbazole and Zinc Pyrithione (ZPTO) through a novel mechanism. The synergy between the herb and the synthetic anti-dandruff agents not only curb dandruff but also prevent drug resistance. The synergy may pose confusion to the pathogen to identify the target molecule and there by develop drug resistance. This is the first study to the best of our knowledge unravel the scientific mystery behind herb – synthetic molecule synergy for prognosis and drug resistance. Method: Zone of inhibition and minimum inhibitory concentration was studied for the individual test materials and market samples. Market samples also tested in different water types by zone of inhibition. A pilot scale study on market products was conducted in human volunteers to understand the aesthetics and hair properties after use. Results: All the studies prove the anti-dandruff activity of the Verdura anti-scaling scalp shampoo and other test samples. The stable efficacy of the Verdura was proven when studied in different waters. Conclusion: Verdura anti scaling scalp shampoo with two anti-dandruff agents Climbazole and Zinc pyrithione along with herbal extracts shows the better activity (at the tested concentrations) and also have superior conditioning benefits.

[Full Text Article]    [Download Certificate]

Powered By WJPMR | All Right Reserved

WJPMR