Abstract

A. Nourreddine, H. Sfaoua*, M. A. Krabch, F. Z. Lahlali, J. Aarab, A. Allam, Y. Moukasse, El Majjaoui, T. Kebdani, H. El Kacemi, N. Benjaafar and R. C. El Moursli

ABSTRACT

Backrgound and purpose: The treatment of locally advanced cervical cancer is external beam radiotherapy to the pelvis alone or in combination with chemotherapy, followed by intracavitary brachytherapy. The objective of this study was to evaluate the role of a new Three-Dimensional Conformal Radiation Therapy (3DCRT) technique in reducing the dose to organs at risk (OARs) as compared with the classic 3DCRT plan which is the box technique with respect to target volume coverage. Methods: We conducted a comparative planning study of forty one patients with cervical cancer treated with radiation therapy, between April 2017 and November 2017 at the National Institute of Oncology in Rabat .Two plans in 3DCRT were done for every patient; one using 6 beams and the second one using the conventional box technique (4 beams). Then, the two plans were compared adopting dose volume histograms (DVH) analysis for the planning target volume (PTV), bladder, rectum and both femoral heads. Results: Comparing different plans of treatment, it was shown that the planning target volume was sufficiently covered in both plans, although, it was demonstrated that the 6 beams conformal radiation therapy technique decreased doses reaching all OARs. Conclusion: From the present study, it is concluded that 6 beams CRT technique spared more adequately OARs than box technique. Hence, it might be a good solution in centres don’t yet have intensity- modulated radiation therapy (IMRT).