Abstract

F.Z. Lahlali*, J. Aarab, A. Allam, H. Sfaoua, S. El Majjaoui, H. El Kacemi and T. Kebdani, N. Benjaafar

ABSTRACT

Background: The neuroendocrine carcinoma of the breast ( NECB) is a very rare type of breast cancer, defined by a common phenotype characterized by the expression of general neuroendocrine markers and sometimes by cell specific hormonal products. Due to the rare nature of this tumor, there are no data from prospective clinical trials on its optimal management. A Early stage tumors are usually treated with the same strategy used for the other types of invasive breast cancer, For metastatic disease, a multimodality therapeutic strategy can be considered on an individual basis. Presentation Of Case: A 59-year-old female who presented a left breast mass. After biopsy, she was diagnosed with a primary NECB with regional lymph node involvement. She was treated by surgery, adjuvant chemotherapy and radiation therapy with a good clinical response. Conclusion: NECB is a heterogeneous group of tumors with different biologic behavior and prognosis. Further research is needed to better understand the behavior of this rare tumor in order to develop a standard approach to treatment.