World Journal of Pharmaceutical
and Medical Research

( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Pharmaceutical and Medical Research and Technology
An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)
ISSN 2455-3301
IMPACT FACTOR: 6.842

ICV : 78.6

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SJIF Impact Factor: 6.842

Abstract

EVALUATION OF METABOLIC AND HUMORAL BLOOD FACTORS IN PATIENTS WITH CHRONIC GENERALIZED PERIODONTITIS ASSOCIATED METABOLIC SYNDROME

*Dr. Jakhongir Abduvakilov and Jasur Rizaev

ABSTRACT

The aim of this study is to evaluate the characteristics of indicators of carbohydrate, lipid metabolism and humoral factors of immunity in the blood plasma in patients with chronic generalized periodontitis (CGP) of moderate degree of combined background metabolic syndrome. The study was conducted in 58 patients with chronic generalized periodontitis of moderate severity combined metabolic syndrome aged 35 to 63 years, as well as 14 volunteers (practically healthy people) with intact periodontal age 25–35 years, who formed the control group (CG). It was revealed that in patients with MS combined with inflammation in periodontal tissues on the background of hyperinsulinemia and dyslipidemia, marked changes in the indices of cellular and humoral immunity are observed. The marked increase in IgG in the blood against the background of a decrease in IgA, in our opinion, is due to increased synthesis of secretory IgA in the oral fluid.

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