World Journal of Pharmaceutical
and Medical Research

( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Pharmaceutical and Medical Research and Technology
An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)
ISSN 2455-3301
IMPACT FACTOR: 6.842

ICV : 78.6

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Abstract

POTENTIAL EFFECTS OF FENUGREEK (TRIGONELLA FOENUM GRAECUM L) ON THE BLOOD GLUCOSE, LIPID PROFILE AND MARKER ENZYMES IN THE FRESH WATER FISH CIRRHINUS MRIGALA

Meera Gopi, Rosmin M. T. and Pawlin Vasanthi Joseph*

ABSTRACT

Diabetes mellitus is a major public health problem in India. It is a very common health problem across the globe. Diabetes mellitus has a huge impact on the quality of life and on an individual's subjective perception of physical, emotional and social well-being. Fenugreek seeds are a rich source of saponins, flavonoids, choline, carotene, essential oils containing trigonelline and other functional elements. The seeds also contain fiber fenugreekine, a component that may have hypoglycemic activity. The objective of the present work is to study the effects of oral administration of Fenugreek seed powder on the biochemical and enzyme profile of the fish. The experimental set up includes one control and three experimental tubs marked as 1g, 3g and 5g. Fishes in the control were fed with the basal diet whereas the experimental fishes were fed with the basal diet having fenugreek of concentrations of 1, 3, 5g/ 100g of basal feed respectively. The experimental set up was maintained for 45 days. The biochemical and enzyme profile of the fish was estimated. It has been observed that fenugreek seeds have a significant lower glycaemic response in fishes. It can be used to decrease the blood glucose levels in diabetic patients and has the ability to reduce Serum Cholesterol, Triglyceride, LDL and able to raise HDL. Fenugreek given before the meal causes a significant reduction in Glycemic index and is beneficial to Non insulin-dependent diabetes mellitus patients for long term control of their blood glucose levels and prevention of hyperglycaemic related complications.

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