World Journal of Pharmaceutical
and Medical Research

( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Pharmaceutical and Medical Research and Technology
An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)
ISSN 2455-3301
IMPACT FACTOR: 6.842

ICV : 78.6

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SJIF Impact Factor: 6.842

Abstract

IN A STUDY ON TYPE 1 DIABETES MELLITUS TREATED WITH METFORMIN

S. V. R. Govardhan Reddy, K. Krishna Vamsi, G. Ramesh, Satheesh S. Gottipati and Dr. P. Srinivasa Babu

ABSTRACT

Metformin is a biguanide anti-hyperglycemic agent used for treating non-insulin dependent diabetes mellitus (NIDDM) It improves glycemic control by decreasing hepatic glucose production, decreasing glucose absorption and increasing insulin-mediated glucose uptake. Metformin may induce weight loss and is the drug of choice for obese NIDDM patients. Retrospective study suggest that use of metformin in patients with type DM reduces glucose concentration, and decreases metabolic syndrome prevalence. Addition of metformin to insulin therapy promote weight control, and reduce insulin dose requirements in patients with type 1 diabetes has been assessed in systematic reviews.

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