World Journal of Pharmaceutical
and Medical Research

( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Pharmaceutical and Medical Research and Technology
An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)
ISSN 2455-3301
IMPACT FACTOR: 6.842

ICV : 78.6

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Abstract

RELATIONSHIP BETWEEN THE USE OF RECOMBINANT HUMAN ERYTHROPOETIN AND MEAN PLATELET VOLUME IN DIALYSIS PATIENTS

Zeki Kemeç, Dr. Ali Gürel*, Mustafa Demir and Ayhan Doğukan

ABSTRACT

Mean platelet volume (MPV) is predictive for many diseases and conditions. The effect of recombinant human erythropoietin (R-HuEPO) on MPV in hemodialysis (HD) or peritoneal dialysis (PD) patients is not well known. We aimed to determine MPV levels in four main groups and two subgroups. The main groups were respectively healthy control (HC), ischemic heart disease (IHD), PD, HD groups. The subgroups were PD and HD groups that received and did not receive r-HuEPO. There were no statistically significant changes in MPV levels in four groups (p> 0.05). On the other hand, MPV levels of r-HuEPO receiving patients were lower than those without (p

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