World Journal of Pharmaceutical
and Medical Research

( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Pharmaceutical and Medical Research and Technology
An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)
ISSN 2455-3301
IMPACT FACTOR: 6.842

ICV : 78.6

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SJIF Impact Factor: 6.842

Abstract

IN SILICO STUDIES ON DENGUE AND RHINO VIRAL STRUCTURAL PROTEINS WITH SELECTED CORIANDRUM SATIVUM L LEAVES CONSTITUENTS

Mahesh K., Nagarjun N., Aniruddha B.S., Ashwini B.M., Murugan Rajadurai and *Balasubramanian Sathyamurthy

ABSTRACT

Dengue virus contains two structural proteins. Rhino virus contains four structural proteins. These are considered to be the most effective for drug designing. Phytochemicals present in Coriandrum sativum L. Functions as aromatizing agents and has relaxant activity in the alimentary tract. They are found to have antibacterial and anticanacerous properties.In this study, the binding efficiency of 4 compounds that are present in the Coriandrum sativum L.with all the selected structural proteins were performed through Insilico methods. Our molecular docking result, we found that Dodecanal has the highest binding affinity with the selected dengue and Rhino structural proteins.

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