World Journal of Pharmaceutical
and Medical Research

( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Pharmaceutical and Medical Research and Technology
An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)
ISSN 2455-3301
IMPACT FACTOR: 6.842

ICV : 78.6

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Abstract

EVALUATION OF ACUTE TOXICITY STUDY AND PHYSICO-CHEMICAL PROPERTIES OF MURUVILI KUDINEER

Abisha A.*, Shanmugapriya C., Meenakumari R. and Muralidharan P.

ABSTRACT

The present study was designed to investigate one such Siddha formulation Muruvili Kudineer. It is herbo mineral formulation of a Siddha medicine and has been used for various herbs and one mineral. To evaluate its safety, acute oral toxicity studies were performed following studies organization for economic co-operation and development (OECD) test guidelines 423. Acute oral toxicity was carried out in sexually mature female wister albino rats (150-200gm) and the animals were treated more than ten times with the therapeutic dose of Muruvili Kudineer and they were observed for toxic signs for 14 days. Acute oral toxicity study showed no lethality in experimental animal with the ten times of therapeutic dose. The Muruvili Kudineer proves to be a safe medicine. The Physico chemical evaluation of Muruvili Kudineer is also proves to be a safe medicine.

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